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Mastering Botox Injection Depth: Key Techniques for Lower Face Treatment

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Mastering Botox Injection Depth: Key Techniques for Lower Face TreatmentDr Tim Pearce
May 22, 2025

The Missing Element in Botox Training

In this master class on depth of injection for botulinum toxins, we’re addressing where most injectors actually go wrong. While most day courses focus extensively on where to inject, they rarely teach how deep to place the product. This critical element of technique can dramatically influence your results, particularly in the lower face where precision is paramount.

In every area of the face, you will get subtly different results depending on the depth of your injection. By understanding optimal depth, you’ll be empowered to inject more accurately, get more predictable results, and experience fewer side effects. This knowledge transforms how you approach botulinum toxin treatments.

The Path to Injection Confidence

There’s a key stage in your path to success as an injector where you suddenly stop thinking about injection points and start to understand how risk and reward changes with every shift in angle, depth, and position of your needle. This awareness is when you become free to create the results you want because you’re automatically guided by this deeper understanding.

Let me share what goes through my mind regarding different injection depths while I’m injecting botulinum toxins and how this guides me to optimize treatment results. This depth awareness is essential for preventing botox complications and achieving consistent outcomes.

Orbicularis Oris: Finding the Right Depth

orbicularis oris muscle anatomyWhat’s the right depth to inject the orbicularis oris muscle? This is a perfect example of how depth affects both results and patient comfort.

If you inject very superficially, you’re in the dermis. This is an extremely sore place to inject, as intradermal injections with toxin will sting considerably. Going a little bit deeper, the injections hurt less. That’s usually where I try to inject – on the surface of the muscle where the receptors are likely to be, or potentially slightly deeper.

However, if you keep injecting deeper still in this region, you’re going to squirt botulinum toxin into a patient’s mouth. This wastes product and delivers no benefit, making depth awareness crucial for both effectiveness and efficiency in your lower face botox technique.

Depressor Anguli Oris: Navigating Muscle Layers

The next critical area is the depressor anguli oris (DAO). This muscle pulls the corner of your mouth down and is layered in a particular way with the depressor labii muscle. If you don’t know which is which, you’ll soon find out when your patient returns unhappy because you’ve affected the wrong muscle.

To properly target the DAO, we need to first establish the position by feeling for the lateral aspect of the contracted muscle. But position is only half the battle – depth is equally crucial for proper DAO botox technique.

Looking at facial anatomy, you can see how depth relates to the depressor labii muscle. The most superficial muscle is the depressor anguli oris, and this is typically where I like to inject. However, if you go deep to it, particularly if you’re inferior, you may go straight through and hit the depressor labii muscle instead.

The consequences of this depth error are significant. The depressor labii pulls your mouth open when you smile, while the depressor anguli oris only pulls the corner of your mouth down. What you get if you go too deep and too medial is that the patient no longer smiles properly in the medial part of the lip. Some practitioners call this the “pey smile” because one side of the mouth moves and the other doesn’t, causing a very obvious asymmetry.

For optimal results with botulinum toxin technique in this area, your injection should pass through the dermis through the hypodermis and then stop, not going all the way through to the level of the periosteum. The exact depth will vary depending on the size of the superficial fat pad above this muscle in each patient.

Developing Depth Awareness

Next time you’re injecting, pay attention to the level that you’re at. Start to think with higher resolution about where your needle tip is likely residing. This awareness is key to becoming a much more proficient and confident injector by understanding what is going on beneath the skin surface.

By understanding where your needle tip is likely to be, you can optimize your technique with different depths, angles, or approaches. This is one of the core elements of becoming really confident with botulinum toxins and will help you prevent botox complications through more precise delivery.

The Importance of Precision

Botox precision comes from understanding not just where to inject, but how deep to place the product. This three-dimensional awareness transforms your approach from simply following injection point maps to truly understanding the facial anatomy you’re treating.

When you master injection depth, you’ll notice:

  • More consistent results
  • Fewer unwanted effects
  • Better patient satisfaction
  • Greater confidence in your technique

This precision is particularly important in the lower face, where muscles overlap and where functional issues can arise from improper depth.

Beyond Basic Training

If you want to really master botulinum toxins, comprehensive training that covers everything from starting out all the way through to advanced full-face treatments is essential. This education should include not just where to inject, but the critical element of how deep to place product in each facial region.

Understanding injection depth is what separates basic injectors from true experts. It allows you to customize treatments based on individual anatomy and to achieve consistent, predictable results that satisfy your patients and build your reputation.

Conclusion: Depth as the Key to Mastery

Mastering injection depth represents one of the core elements of becoming a truly proficient and confident botulinum toxin injector. While basic training often focuses primarily on where to inject, understanding how deep to place product is equally important for achieving optimal results.

By developing your awareness of tissue layers and muscle relationships, you’ll be empowered to make more precise injection decisions. This precision leads to better outcomes, fewer complications, and greater patient satisfaction with your lower face botox treatments.

Remember that the journey to mastery involves continuous learning and refinement. Each treatment provides an opportunity to enhance your depth awareness and technique. By paying attention to these subtle but crucial aspects of injection, you’ll distinguish yourself as a practitioner who delivers consistently excellent results through proper botulinum toxin technique.

Free Guide to Neurotoxin Injection Patterns

Want to learn the best toxin patterns for the upper face based on your patients unique anatomy? Get our comprehensive guide to neurotoxin injection patterns to inject based on anatomy, not just points.

BOTOX (Botulinum Toxin) eLearning Courses

If you want to increase your confidence in botulinum toxin injections, or learn how to avoid and handle complications, Dr Tim Pearce offers two comprehensive courses that are highly rated by our delegates:

  • BOTOX® Foundation Course
  • Botulinum Toxin Complications Mastery

Both give CPD and certificates on completion.

In addition, browse our FREE downloadable resources on complications.

Dr Tim Pearce eLearning

Dr Tim Pearce MBChB BSc (Hons) MRCGP founded his eLearning concept in 2016 in order to provide readily accessible BOTOX® and dermal filler online courses for fellow Medical Aesthetics practitioners. His objective was to raise standards within the industry – a principle which remains just as relevant today.

Our exclusive video-led courses are designed to build confidence, knowledge and technique at every stage, working from foundation level to advanced treatments and management of complications.

Thousands of delegates have benefited from the courses and we’re highly rated on Trustpilot. For more information or to discuss which course is right for you, please get in touch with our friendly team.

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